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003
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Oleanolic acid
Specification *8%
Synonym Aralia acid Oleanol, Caryophyllia, Astrantig
Synonym Aralia acid Oleanol, Caryophyllia, Astrantigeninc, Giganteumgeninc
C A S No. *******1
Source: is a pentacyclic triterpenoids, in order to free body and the form of glycosides found in a variety of plants. The main source of Oleaceae plants extract olea europaea l. leaf; ligustrum lucidum ait. Fruits; Gentianaceae plants swertia mileensis tnhe et wlshi the whole plant; s. mussotii franch.; UMBELLIFERAE astrantia major l. of the leaves, root; Araliaceae aralia chinensis l. The root bark and bark; Cucurbitaceae hemsleya macrosperma cywu, hemsleya amabilis diels, hemsleya chinensis cogn. (the roots.
Molecular Formula C*0H*8O3
Molecular Weight **6.*1
Physical properties of white needle crystal (ethanol); odorless,
tasteless, soluble in methanol, ethanol, benzene, ethyl ether,
acetone and chloroform, practically insoluble in water, acid-base
pairs are unstable. Melting point: **8 ~ **0 , [±] *0D **8 ° to **8
° (C = 0.*5, chloroform).
Composition: pentacyclic triterpenoids Categories
Oleanolic acid is a triterpenoid compound that is widespread in
nature, in particular it occurs in leaves of Olea europea L.
(Oleaceae). It has been long recognized to have hepatoprotective,
antiinflammatory, and antihyperlipidemic properties. Recently
oleanolic acid has been noted for its antitumor-promotion effect.
Little is known about the antiviral activity of this compound. In
this study the effect of oleanolic acid on the growth of HIV*1 in
cultures of human peripheral blood mononuclear cells (PBMC) was
investigated Both oleanolic acid and ursolic acid are effective
in protecting against chemically induced liver injury in
laboratory animals. Oleanolic acid has been marketed in China as
an oral drug for human liver disorders. The mechanism of
hepatoprotection by these two compounds may involve the
inhibition of toxicant activation and the enhancement of the body
defense systems. Oleanolic acid and ursolic acid have also been
long-recognized to have antiinflammatory and antihyperlipidemic
properties in laboratory animals, and more research is warranted
to develop a therapy for patients. Recently, both compounds have
been noted for their antitumor-promotion effects, which are
stimulating additional research in this field. Oleanolic acid and
ursolic acid are relatively non-toxic, and have been used in
cosmetics and health products. The possible mechanisms for the
pharmacological effects and the prospects for these two compounds
are discussed.
Country: | China |
Model No: | 003 |
FOB Price: | Get Latest Price |
Place of Origin: | - |
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