Puerarin(Kudzu) root extract Isoflavones 40% UV/HPLC

**0% Natural Kudzu Root Extract/ Puerarin *0%, *0%, *0%, *8%  

Latin Name: Pueraria lobata (Wild.) Ohwi (Root) 
Part of Used: Root 
Active Ingredients: Puerarin, Isoflavones 
CAS NO: ********0 (Puerarin) 
Specification: Puerarin *0%, *0%, *0%, *8% by HPLC; Isoflavones *0%**0% UV
 Appearance: Yellow brown Fine Powder(Pueraria Isoflavones), White Crystal Powder (Puerarin) 
Test Method: HPLC /UV 

Human studies with kudzu root extract

Pharmacokinetic profile of the isoflavone puerarin after acute and repeated administration of a novel kudzu extract to human volunteers.

J Altern Complement Med. ***6. This study was undertaken to assess the pharmacokinetic profile of puerarin, the major isoflavone found in a kudzu (Pueraria lobata) extract after acute and repeated administration. Participants were given either single or repeated doses of kudzu extract, and blood samples were collected for either 8 or *2 hours for subsequent pharmacokinetic analyses of puerarin. Puerarin was found to be rapidly absorbed via the oral route, reach peak levels at 2 hours, and have a half-life of approximately 4.3 hours. The elimination half-life was not significantly altered after repeated administration. A formulation of kudzu extract delivers a large amount of the principal isoflavone in a rapid manner. The elimination rate constants and the mono-exponential decline in blood levels suggest that a one compartment model adequately explains how puerarin is handled by the body. Three times a day dosing is recommended as accumulation will not occur, and plasma levels remain at levels that are biologically active, even 8 hours after the last steady-state dose.