Product Description
Description
Human Keratinocyte
growth factor*2 (KGF*2 or FGF**0) is a novel human protein that
stimulates the repair of injured mucosal tissues. KGF*2 directly
promotes wound-healing by stimulating the proliferation,
migration and differentiation of epithelial cells, and has direct
chemotactic effects on tissue remodeling. KGF*2 also appears to
result in less scarring.
Recombinant Human
KGF*2 produced in E.Coli is a single, non-glycosylated
polypeptide chain containing **0 amino acids with molecular
weight of about *9.3kD. Recombinant human KGF*2 is highly related
to KGF*1(FGF*7) and binds to the same receptor as KGF*1 and
shares *7% sequence homology. Recombinant KGF*2 is purified by
proprietary chromatographic techniques.
Source：Escherichia
Coli.
Physical
Appearance：Sterile
Filtered White lyophilized (freeze-dried)
powder.
Formulation：Lyophilized
from a concentrated (1mg/ml) solution in water containing *0mM
Sodium Phosphate buffer, pH 7.4 , *0 mM
NaCl.
Solubility：It
is recommended to reconstitute the lyophilized KGF *2 in sterile
*8MΩ-cm　H2O not less than **0ug/ml, which can
then be further diluted to other aqueous
solutions.
Stability：Lyophilized
KGF*2 although stable at room temperature for 3 weeks, should be
stored desiccated below **8℃ . Upon reconstitution KGF*2 should
be stored at 4℃ between **7 days and for future use below **8℃ .
For long term storage it is recommended to add a carrier protein
(0.1% HSA or BSA).
　　Please avoid
freeze-thaw cycles.
Amino-Acid
Sequence :The sequence of the first five N-terminal
amino acids was determined and was found to be
Met-Ala-Leu-Gly-Asp.
Dimers and
aggregates :Less than 1% as determined by silver-stained
SDS-PAGE gel analysis.
Biological
Activity :Recombinant human KGF*2 is fully biologically
active when compared to standards. The specific activity is about
1.0 x *0 6 Units/mg.
| Country: |
China |
| Model No: |
005
|
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(Negotiable)
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