Rutin NF11 DAB10

Product Description

Rutin NF*1 DAB*0 Item No.: NL*****2 / NL*****1 Grade: NF*1/ DAB*0 CAS NO.: *******4 Molecular formula: C*7H*0O*6 Molar mass: **0.***5 Botanical origin: Sophora japonica L. Appearance: Greenish-yellow powder Type of extraction: Ethanol/water Solubility : Practically insoluble in chloroform and ether Infinitesimally soluble in cool water Sparingly soluble in boiling ethanol and boiling water Dissolves in solution of alkali hydroxides Benefits: Rutin inhibits platelet aggregation, making the blood thinner and improve circulation. Has anti-inflammatory activity. Rutin inhibits aldose reductase activity. Aldose reductase is an enzyme normally present in the eye and elsewhere in the body. It helps change glucose (sugar - glucose) into a sugar alcohol called sorbitol. Too much sorbitol trapped in eye and nerve cells can damage these cells, leading to retinopathy and neuropathy. Substances that prevent or slow the action of aldose reductase are being studied as a way to prevent or delay these complications of diabetes. Aldose reductase is the first enzyme in the sorbitol pathway. This pathway is responsible for the conversion of glucose to sorbitol, and of galactose to galactitol. Under conditions of hyperglycemia, sorbitol accumulation occurs. Aldose reductase inhibitors prevent the accumulation of intracellular sorbitol. Whether rutin can help reduce the rate of glaucoma is not clear. Rutin inhibits platelet aggregation as well as decreasing capillary permeability, making the blood thinner and improving circulation.[citation needed] Rutin shows anti-inflammatory activity in some animal and in vitro models.