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Contact Person haoyu
Xiamen, Fujian
Product name:conolidine
CAS: **********1
Molecular formula: C*7H*8N2O
Description:Conolidine is an alkaloid. Preliminary reports suggest
that it could provide analgesic effects with few of the detrimental
side-effects associated with opioids such as morphine, though at
present it has only been evaluated in mouse models.
Conolidine was first isolated in ***4 from the bark of the
Tabernaemontana divaricata (Crepe jasmine) shrub which is used in
traditional Chinese medicine.
A method for creating synthetic conolidine from a commercially
available acetyl-pyridine in 9 steps was developed by Micalizio,
Bohn, and coworkers in ***1. This synthetic route allows access to
either enantiomer (mirror image) of conolidine via an early
enzymatic resolution. Notably, both enantiomers of the synthetic
compound show analgesic effects.
Country: | China |
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