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1000 Kilogram Minimum Order
Country:
China
Model No:
-
FOB Price:
Place of Origin:
China
Price for Minimum Order:
-
Minimum Order Quantity:
1000 Kilogram
Packaging Detail:
25kg per drum
Delivery Time:
Prompt
Supplying Ability:
50000 Kilogram per Month
Payment Type:
-
Product Group :
Contact Person Ms. Lily
No.988, Zhongchun Road, Minhang District, Shanghai, Shanghai
Croscarmellose Sodium
Product name:
Croscarmellose Sodium,Crosslinked Carboxymethylcellulose
Sodium
CAS
NO.74811-65-7
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Croscarmellose
Sodium is tasteless, white or grayish white free flowing powder,
used as disintegrating agent in tablets, capsules and granules, it
is usually regarded as a basically non-toxic and non irritating
excipient. Common dosage in tablets: 0.5% ~
5.0%
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Solubility:
insoluble in water, but the volume rapidly expands to 4-8 times of
the original volume after contacting with water, insoluble in
absolute ethanol or ether
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Stability:
stable in nature, but hygroscopic.
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CroscarmelloseSodium is
used as disintegrating agent for tablets, capsules and granules in
oral preparations. It has disintegrating effect by capillary and
swelling. This product is characterized by good compressibility and
strong disintegrating power. In the tablet production process, this
product is suitable for the direct tablet pressing process and the
wet granulation tablet pressing process. In the wet granulation
process, the crosslinked sodium carboxymethyl cellulose can be
added in the wetting stage or in the drying stage (particle
addition and particle addition), but the effect of addition is
better than that of internal addition. Some studies have shown that
the swelling of crosslinked sodium carboxymethyl cellulose in water
> low substituted sodium carboxymethyl cellulose > hydrated
microcrystalline cellulose and other common disintegrating agents;
Whether the product is added internally or externally, the
brittleness of the tablets will not be affected, and the
disintegration time limit and release effect of the tablets
prepared with it will not change over time. When used as
disintegrating agent, the dosage can reach 5.0% (w/w), but it is
usually 2.0% (w/w) in direct tablet pressing process and 3.0% (w/w)
in wet granulation process.Â
Country: | China |
Model No: | - |
FOB Price: | Get Latest Price |
Place of Origin: | China |
Price for Minimum Order: | - |
Minimum Order Quantity: | 1000 Kilogram |
Packaging Detail: | 25kg per drum |
Delivery Time: | Prompt |
Supplying Ability: | 50000 Kilogram per Month |
Payment Type: | - |
Product Group : | Pharmaceutical raw material |