Basic Info.
Certification
GMP, HSE, ISO ***1, USP, BP
Transport Package
Aluminum Foil Bag Inside, Then Waterproof Bag
Product Description
Product Description
|
Prodcut name
|
melatonin
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|
Standard packing material
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Aluminum foil bag inside, then waterproof bag
or carton
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Appearance
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White white
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Purity
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*9%
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Storage
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Preserve in tight,light-resistant containers
in a cool place
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Precautions while taking melatonin
1. Strictly follow the people who take it,
the dosage and the time of taking it.
2. Don't be superstitious about imported melatonin
products. Melatonin is a health food.
Whether it is a domestic or foreign imported raw
material, as long as the quality standard is
qualified, the effect of taking it is the
same.
3, taking melatonin can not take aspirin at the same
time.
4. It is best not to smoke when taking
melatonin, because smoking can destroy
melatonin. Also, don't drink a
lot.
5. The health care function of melatonin approved by
the Ministry of Health is only to improve sleep
function, and the literature reports on other health
care functions of melatonin need to be further
verified.
unsuitable people
Melatonin does have a good effect on improving sleep and immune
regulation, but it is not suitable for
everyone, and taking it improperly is
counterproductive. The following people should take
melatonin with caution.
1. Minors
2. Pregnant women
3. Patients with heart and brain disease
4. Liver and kidney insufficiency
5. Those who are allergic to alcohol
The main purpose
anti aging
Free radicals may be generated during enzymatic and non-enzymatic
reactions in the body, and free radicals are closely
related to aging. The generation and elimination of
free radicals in the normal body are in a dynamic
balance. Once this balance is broken, free
radicals will cause damage to biological macromolecules such as
lipids, proteins, and nucleic
acids, resulting in the destruction of cell structures
and the aging of the body. Melatonin protects cell
structure, prevents DNA damage, and reduces
peroxide levels in the body by scavenging free
radicals, anti-oxidation and inhibiting lipid
peroxidation. The study by Russel et al.
found that melatonin protected *9% of DNA damage
caused by safrol e, a carcinogen that damages DNA by
releasing free radicals, in a dose-response
relationship. Melatonin has obvious antagonistic
effect on the peroxidation caused by exogenous poisons
(such as paraqua t) and the tissue damage
caused by free radicals. Melatonin can also reduce the
content of LPO in the brain, and its effects are
basically the same in different regions of the brain,
such as the cerebral cortex, cerebellum,
hippocampus, hypothalamus,
striatum, etc., and they are all
in a dose-dependent manner. But different strains of
rats such as Sprague-Dawlay and Wistar rats have different
sensitivity to melatonin.
fight tumor
In vitro studies by Vijayalaxmi et al.
(***5) found that melatonin had a significant
protective effect on the chromosomal damage of human peripheral
lymphocytes caused by γ-rays (**0cGy) of
**7Cs, and showed a dose-response
relationship; physical and chemical effects on free
radicals Mutagenicity and carcinogenicity are
antagonistic. In vitro tests have shown that melatonin
also has a protective effect on the mutagenicity caused by
self-immobilization C. Melatonin reduces the formation
of DNA adducts induced by chemical carcinogens (safrol
e) and prevents DNA damage. Jianjun Yan et
al. studied the antitumor effect of melatonin on H*2
liver cancer mice, and found that it can inhibit tumor
growth and prolong the survival time of tumor-bearing
mice, and has obvious synergy with IL*2.
Danforth et al measured the **-hour plasma melatonin levels of
women in normal, breast cancer, and breast
cancer-prone patients, respectively, and
found that normal women had a circadian rhythm; the
circadian rhythm of breast cancer patients was significantly
related to the amount of steroid receptors in the primary tumor
related. In patients with positive estrogen
(ER) or progesterone (PR)
receptors, the mean day-to-night plasma melatonin was
significantly lower than that in patients with ER or PR negative
tumors, and was significantly negatively correlated
with the amount of ER or PR receptors in the primary tumor
, indicating that melatonin has a certain correlation
with hormone-dependent human breast cancer. Melatonin
promotes endogenous granulocyte/macrophage-promoting
accumulation factor production by myeloid T-cells and can be used
as an adjuvant therapy for tumors.
sleep
It can shorten the time to wake up before going to bed and the
time to fall asleep, the quality of sleep,
the number of awakenings during sleep are significantly
reduced, the light sleep stage is shortened,
the deep sleep stage is prolonged, and the wake-up
threshold the next morning decreases. There is a
strong function of adjusting the time difference.
[1] Mainly used in whitening and moisturizing
cosmetics, and also commonly used in hair growth
products. Extensive research has been carried out on
the biological functions of melatonin at home and
abroad, especially as a dietary supplement,
and it has been shown that it has many physiological functions
such as promoting sleep, regulating jet lag,
anti-aging, regulating immunity, and
anti-tumor. The health care function of melatonin at
home and abroad involves regulating endocrine
(suppressing ovulation), protecting
against encephalitis virus infection, reducing
mortality after infection, treatment of AIDS,
and cardiovascular protection.
Product Description
FAQ
Q1: MAY I GET ONE SAMPLE BEFORE PLACING
ORDER?
Re: Yes, we'd like to provide sample for
you. For those normal products, you just
need to bear the freight; for those high value
products, you just need to freight and a ite product
cost. When we both cooperate for some times or when
you are our VIP customer, free sample will be offered
when you need.
Q2: WHICH PAYMENT IS AVAIL ABLE FOR YOUR
COMPANY?
Re: In order to prompt our cooperation,
there are some payment methods for your choice.
T/T(USD), West- erm
union, Paypal, Credit card,
Alipay or Alibaba trade insurance all is ok. You can
choose the one which is convenient for you.
Q3: HOW AND WHEN CAN I GET MY GOODS AFTER
PAYMENT?
Re: For small quantity products, they will
be delivered to you by intermational
courer(DHL, FedEx, TIT,
EMS, etc.) or by air.
Usually it will cost **5 days that you can get the goods after
delivery. For large quantity products,
shipment is better. It will cost days to weeks to
come to your destination port, which depends on where
the port is.
Q4: IS THERE ANY POSSIBLE TO USE MY APPOINTED LABEL
OR PACKAGE?
Re: Sure. If needed, we'd like
to use label or package according to your
requirement.
Q5: HOW CAN YOU GUARANTEE THE GOODS YOU OFFER IS
QUALIFIED?
Re: We always believe honesty and responsibility are
basis of one company, so whatever products we provide
for you all are high qualifed. If the goods can't come
to the quality we promise, you can ask for
refund.
