FOB Price
Get Latest Price|
10 Gram Minimum Order
Country:
China
Model No:
-
FOB Price:
Place of Origin:
China
Price for Minimum Order:
-
Minimum Order Quantity:
10 Gram
Packaging Detail:
Packed in food-grade plastic bag inside and aluminum-foil bag outside
Delivery Time:
15 days for ready
Supplying Ability:
10 Kilogram per Month
Payment Type:
T/T, L/C, Western Union, PayPal
Product Group :
Contact Person QA
No.125 kangtian Road, Changsha, Hunan
PTC**4 targets genetic disorders caused by nonsense mutations. [1]
PTC**4 is an orally bioavailable compound that promotes of the
human CFTR-G**2X nonsense allele in a CF mouse model. [2]
Effectiveness of PTC**4 treatment of cystic fibrosis caused by
nonsense mutations: a prospective phase II trial.
[3]
PTC**4 induces dose-dependent suppression of premature
translational termination without concomitant effects on normal
termination or mRNA decay. [1]
In safety pharmacology studies in rats and dogs, oral
administration of PTC**4 induces no adverse neurological,
pulmonary, or cardiovascular effects at doses through ***0 mg/kg.
In toxicology studies in rats and dogs at oral doses through ***0
mg/kg for *8 days, PTC**4 has shown good tolerability.
[1]
The minimal concentration of PTC**4 showing discernable readthrough
was 0.**0.1 mM (2.**8 ng ml*1), whereas the concentration promoting
maximal activity was approximately 3 mM(**2 ng ml*1). [1]
| Country: | China |
| Model No: | - |
| FOB Price: | Get Latest Price |
| Place of Origin: | China |
| Price for Minimum Order: | - |
| Minimum Order Quantity: | 10 Gram |
| Packaging Detail: | Packed in food-grade plastic bag inside and aluminum-foil bag outside |
| Delivery Time: | 15 days for ready |
| Supplying Ability: | 10 Kilogram per Month |
| Payment Type: | T/T, L/C, Western Union, PayPal |
| Product Group : | intermediate |
