Caffeine Anhydrous

ANALYSIS

SPECIFCATION

RESULTS

Appearance

White crystalline powder

Complies

Identification

Complies

Complies

Melting point

**4°C***9°C (BP)

**5.9~**6.7°C

Appearance of solution

Clear and colorless (BP)

Complies

Assay (on dry basis, HPLC)

*8.5%***1.0% (USP)

*9.9%

Acidity (0.*1mol/L NaOH, ml)

≤0.2 (BP)

<0.2

Organic impurities

- individual impurity

≤0.1% (USP)

0.1%

- Total impurities

≤0.1% (USP)

0.1%

Sulfate

≤**0 ppm (BP)

<**0 ppm

Heavy metals (as Pb)

≤*0ppm(USP)

<*0ppm

Loss on drying

≤0.5% (BP)

0.*9%

Residue on ignition

≤0.1% (USP)

0.*6%

Residual solvents (Chloroform)

≤*0 ppm

<*0 ppm

Related substances

- Each impurity A,B,C,D,E,F

≤0.*0%(BP)