Emamectin Benzoate 0.5% +chlorbenzuron 24.5% SC compound pesticide made in China

Product Description

Emamectin Benzoate 0.5% +chlorbenzuron *4.5% SC compound pesticide made in China

NOMENCLATURE

emamectin benzoate

CAS RN [**********8]; formerly [**********4] and [**********2]  Development codes MK **4 (Merck & Co.)  

 

emamectin

Common name emamectin (BSI, pa E-ISO, ANSI); emamectine ((f) pa F-ISO)

IUPAC name A mixture containing *0% of (*0E,*4E,*6E,*2Z)-(1R,4S,5'S,6S,6'R,8R,*2S,*3S,*0R,*1R,*4S)*6'-[(S)-sec-butyl]**1,**-dihydroxy*5',*1,*3,**-tetramethyl**-oxo*3,7,**-trioxatetracyclo[*5.6.1.*4,8.**0,*4]pentacosa**0,*4,*6,**-tetraene**-spiro*2'-(5',6'-dihydro*2'H-pyran)***-yl 2,*-dideoxy**-O-methyl**-O-(2,4,*-trideoxy**-O-methyl**-methylamino-a-L-lyxo-hexopyranosyl)-a-L-arabino-hexopyranoside and *0% of (*0E,*4E,*6E,*2Z)-(1R,4S,5'S,6S,6'R,8R,*2S,*3S,*0R,*1R,*4S)**1,**-dihydroxy*6'-isopropyl*5',*1,*3,**-tetramethyl**-oxo*3,7,**-trioxatetracyclo[*5.6.1.*4,8.**0,*4]pentacosa**0,*4,*6,**-tetraene**-spiro*2'-(5',6'-dihydro*2'H-pyran)***-yl 2,*-dideoxy**-O-methyl**-O-(2,4,*-trideoxy**-O-methyl**-methylamino-a-L-lyxo-hexopyranosyl)-a-L-arabino-hexopyranoside  

Chemical Abstracts name (4"R)**-O-demethyl*4"-deoxy*4"-(methylamino)avermectin A1a + (4"R)**-O-demethyl***-de(*-methylpropyl)*4"-deoxy*4"-(methylamino)***-(*-methylethyl)avermectin A1a (9:1)  

CAS RN [**********2]; formerly [**********4] and [**********6]  

 

 

emamectin

Mol. wt. **6.1 (B1a); **2.1 (B1b)  M.f. C*9H*5NO*3 (B1a); C*8H*3NO*3 (B1b)  

 

COMMERCIALISATION

Production Isolated from fermentation of Streptomyces avermitilis, a naturally occuring soil Actinomycete.  History Discovery and initial development was by Merck & Co., Inc. (now  AG). First sales in Israel and Japan in ***7.  Manufacturers Merck & Co.

 

APPLICATIONS

emamectin benzoate

Biochemistry Acts by stimulating the release of g-aminobutyric acid, an inhibitory neurotransmitter, thus causing paralysis.  Mode of action Non-systemic insecticide which penetrates leaf tissues by translaminar movement. Paralyses the lepidoptera, which stop feeding within hours of ingestion, and die **4 dat.  Uses For control of Lepidoptera on vegetables, brassicas and cotton, at up to *6 g/ha, and in pine trees, at ***5 g/ha. Formulation types EC; SG.  Selected products: 'Banlep' (); 'Denim' (); 'Proclaim' ()

 

ANALYSIS

Product and residues determined by hplc. Details available from .  

 

MAMMALIAN TOXICOLOGY

emamectin benzoate

Oral Acute oral LD*0 for rats ****9 mg/kg.  Skin and eye Acute dermal LD*0 for rabbits >***0 mg/kg. It is not irritant to skin, and has no sensitising potential.  Inhalation LC*0 (4 h) for rats 2.***4.*4 mg/m3.  NOEL (1 y) for dogs 0.*5 mg/kg b.w.  ADI 0.***5 mg/kg.  Other Not tumorigenic.  Toxicity class WHO (a.i.) II (company classification)  

 

ECOTOXICOLOGY

emamectin benzoate

Birds Acute oral LD*0 for mallard ducks *6, bobwhite quail **4 mg/kg. Dietary LC*0 (8 d) for mallard ducks **0, bobwhite quail ***8 ppm.  Fish LC*0 (*6 h) for rainbow trout **4, sheepshead minnow ***0 mg/l.  Daphnia LC*0 0.*9 mg/l.  Bees Toxic to bees.  Worms LC*0 >***0 mg/kg dry soil.  Other beneficial spp. Safe to a wide range of beneficial insects, due rapid breakdown of the a.i., limiting contact activity to <*8 h.  

 

ENVIRONMENTAL FATE

Animals Emamectin benzoate is partially metabolised but rapidly cleared (DT*0 following oral dosing ****1 h), indicating that it has no potential for bioaccumulation.  Plants Metabolism has been investigated in lettuce, cabbage and sweet corn. It is non-systemic, and rapidly degrades in sunlight to various complex residues in which undegraded parent is the only significant residue. The residues were very low.  Soil/Environment Rapidly degraded.